Voxelotor in sickle cell disease: There’s HOPE in the HOPE trial
Following receipt of an email from The NEJM, about the notable articles of 2019, one paper stood out for me…
Hydroxyurea in sickle cell disease: Recommendations of use.
We’ve enjoyed three articles about hydroxyurea so far. Let’s summarize the recommendations for the administration of hydroxyurea alias Hydroxycarbamide. These…
Hydroxyurea in sickle cell disease: Administration and Adverse Effects: Part 3
No drug is safe to administer to any patient, not even vitamin supplements. And because hydroxyurea is an anticancer per…
Hydroxyurea in sickle cell disease: These features make it a perfect therapeutic agent: Part 2.
If you’ve read the previous article about the vital facts about hydroxyurea in sickle cell disease, you now have an…
Hydroxyurea in sickle cell disease: What You Need To Know: Part 1
It is not very common that a drug like hydroxyurea is so exceptionally incredible, yet it has not gained as…
Chronic eye complications in sickle cell disease: Everyone has a role to play.
We said in the previous articles that the management of sickle cell disease requires a multidisciplinary approach with the primary…
Hepatobiliary Complications in Sickle Cell Disease: Recommendations
Hepatobiliary complications in sickle cell disease range from gallbladder stones to life-threatening acute hepatic sequestration. For simplicity, we classify them…
Stuttering priapism in sickle cell disease: Recommendations
Stuttering priapism – no one has ever wanted surprising erections – so every effort must be made to prevent them,…
Let’s talk about avascular necrosis of the femoral head in sickle cell disease.
Avascular necrosis (AVN) is one of the most common causes of chronic pain in sickle cell disease. We define it…
Pulmonary hypertension in sickle cell disease:
Pulmonary hypertension is one of those chronic complications of sickle cell disease that you only hear on ward rounds or…